"Cannot start Microsoft Outlook. Cannot open the Outlook window. The information store could not be opened."  [Office 2013/Office 365]

So here is the error in Outook 2013

"Cannot start Microsoft Outlook. Cannot open the Outlook window. The information store could not be opened."

Very Very frustrating having spent three hours today reading forums, installing, reinstalling etc.

HELP?

1) I have completely un-installed and reinstalled Outlook 2013 (And also all of Office 2013)

2) Have blown away all profiles and created new ones.

3) Have blown away all Outook data files and starting from scratch

4) Have run /resetnavpane............in an attempt to rebuild the navigation pane

5) Have gone into Registry and deleted all remnants of previous Outlook installs, HKey_Local, System Current config......Office etc.

6) I have spent hours reading online fixes/technet forums etc..............to no avail.

Please give more suggestions.

Thanks

Phil H   Charlotte, NC

February 15th, 2015 4:15pm

Hi,

Basically you have tried a lot but the issue still exists, now one more suggestion I can provide is to make sure Outlook is not configured to run in Compatibility Mode:

Take Windows 7 for example, in Start -> Type "Outlook" in the search box -> Right click on the "Outlook 2013" shortcut -> Click Properties -> Under Compatibility tab -> Make sure "Run this program in compatibility mode for" is clear.

This method has resolved the issue for some users in this thread below:

http://answers.microsoft.com/en-us/office/forum/office_2007-office_install/cannot-start-microsoft-office-outlook-error-cannot/e75265b4-044f-4d92-a078-1acbf9ae34d6

I hope the information is helpful.

Regards,

Melon Chen
TechNet Community Support

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February 15th, 2015 10:28pm

need a little more information.
which account type are you using (exchange , imap , pop3 or others)
if exchange you might wish to contact the exchange administrator.

February 15th, 2015 10:59pm

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